Clinical Laboratory Improvement Amendments -- Joint Commission Standards -- Notes -- Chapter 5: Regenerative Medicine in the Canine: A Translational Model -- The Use of Biologics in the Canine -- Platelet-Rich Plasma -- The Optimal PRP Product -- Platelet-Rich Plasma in the Canine -- Administration of PRP -- Stem Cell Therapy -- Stem Cell and PRP Combination Therapy -- Administration of Stem Cell Therapy -- Rehabilitation Therapy Following Stem Cell Therapy -- Hyaluronic Acid -- Hyaluronic Acid in the Canine -- Administration of Hyaluronic Acid -- Biologics for OA -- Biologics for Soft Tissue Injury -- Stem Cell Therapy for Soft Tissue Injury -- Stem Cell and PRP Combination Therapy for Soft Tissue Injury -- Commonly Treated Soft Tissue Injuries in the Canine -- Rotator Cuff Injury in the Canine -- Iliopsoas Tendinopathy -- Achilles Tendinopathy -- Cranial Cruciate Ligament Injuries -- Stifle Collateral Ligament Injuries -- Conclusion -- References -- Chapter 6: Principles of Platelet-Rich Plasma and Stem Cells: From Platelets to Cytokines -- Phases of Tissue Healing Versus Pathologic Degeneration -- Tissue Regeneration and Orthobiologics -- Basics of PRP Therapy -- Preparation of PRP -- Basics of Stem Cell Therapy -- Mesenchymal Stem Cells -- Ethical Considerations -- Conclusion -- Acknowledgment -- References -- Chapter 7: Scientific Evidence of Platelet-Rich Plasma for Orthopedic Conditions: Basic Science to Clinical Research and Application -- Basic Science -- Wound Healing -- Components of PRP -- Considerations for Use of PRP -- Evidence for Musculoskeletal Disorders -- Tendon -- Ligament -- Muscle -- Cartilage -- Intervertebral Disc -- Future Work -- Conclusion -- References -- Chapter 8: Platelet-Rich Plasma to Enhance Orthopedic Procedures -- What is Platelet-Rich Plasma? -- Definition -- How Does PRP Work? -- Attributes of PRP Preparations