Concepts of health and disease -- Cell and tissue characteristics -- Cellular adaptation, injury, and death -- Genetic control of cell function and inheritance -- Genetic and congenital disorders -- Neoplasia -- Stress and adaptation -- Disorders of fluid, electrolyte, and acid-base balance -- Inflammation, tissue repair, and wound healing -- Mechanisms of infectious disease -- Innate and adaptive immunity -- Disorders of the immune response, including HIV/AIDS -- Organization and control of neural function -- Somatosensory function, pain, headache, and temperature regulation -- Disorders of motor function -- Disorders of brain function -- Sleep and sleep-wake disorders -- Disorders of thought, emotion, and memory -- Disorders of visual function -- Disorders of hearing and vestibular function -- Blood cells and the hematopoietic system -- Disorders of hemostasis -- Disorders of red blood cells -- Disorders of white blood cells and lymphoid tissues -- Structure and function of the cardiovascular system -- Disorders of blood flow and blood pressure regulation -- Disorders of cardiac function, and heart failure and circulatory shock -- Disorders of cardiac conduction and rhythm -- Structure and function of the respiratory system -- Respiratory tract infections, neoplasms, and childhood disorders -- Disorders of ventilation and gas exchange -- Structure and function of the kidney -- Disorders of renal function -- Acute kidney injury and chronic kidney disease -- Disorders of the bladder and lower urinary tract -- Structure and function of the gastrointestinal system -- Disorders of gastrointestinal function -- Disorders of hepatobiliary and exocrine pancreas function -- Alterations in nutritional status -- Mechanisms of endocrine control -- Disorders of endocrine control of growth and metabolism -- Structure and function of the male genitourinary system -- Disorders of the male reproductive system -- Structure and function of the female reproductive system -- Disorders of the female reproductive system -- Sexually transmitted infections -- Structure and function of the musculoskeletal system -- Disorders of musculoskeletal function: trauma, infection, neoplasms -- Disorders of musculoskeletal function: developmental and metabolic disorders, activity intolerance, and fatigue -- Disorders of musculoskeletal function: rheumatic disorders -- Structure and function of the skin -- Disorders of skin integrity and function.